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Jobbtitel:
Postdoctoral fellows in yeast as a model for aging

Arbetsbeskrivning:
The University of Gothenburg tackles society’s challenges with diverse knowledge. 38 000 students and 6 000 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future. The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them The Institute is composed of the following five departments: • The Department of Infectious Diseases • The Department of Microbiology and Immunology • The Department of Pathology and Genetics • The Department of Clinical Chemistry and Transfusion Medicine • The Department of Medical Biochemistry and Cell Biology At present, the institute has about 380 employees and approximately 400 million SEK in total assets. Subject area Yeast as a model for aging and age-related proteoptahies. Subject area abstractJV_description This project aims to decipher how yeast cells manages misfolded proteins, including human disease proteins, through their protein quality control systems (PQC) in different irganelles and how these systems communicate with each other. Further, the project will analyze how cellular aging is affecting the activity of these systems and how this, in turn, may influence the buildup of cytotoxic aggregates, including model disease proteins of human neurological disorders, during cellular aging. Job assignments The postdoctoral project consists of research and supervision. The research entails in-depth analysis of yeast PQCand protein aggregation using molecular, genetic, and biochemical tools. Microscopy including single-cell, as well as, ensemble analysis is a prominent part of the assignment. The project will also include the construction of new yeast strains suitable for microscopic analysis of protein aggregation and new genetic screens. Eligibility An achieved doctoral degree is compulsory for a position as postdoctor at Göteborg University. The doctoral thesis shall be in a relevant area according to the specific position stated here. Since a position as postdoctor aims to give new holders of the doctorate the opportunity mainly to strengthen and develop their scholarly proficiency, we aim for those who have a doctoral degree not older than 3 years counting from last date of application. The qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance. Assessment We are looking for a scholar with well-documented merits in yeast (Saccharomyces cerevisiae) molecular biology, including genetics and strain constructions. The successful applicant should have experience in microscopy including single-cell analysis. Documented (peer-reviewed original papers) expertise in working with yeast protein quality control/protein aggregation is considered advantageous.  Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance. Employment The employment is fulltime änd temporary, two years, with placement at the Institute of Biomedicine. For further information: Please contact professor Thomas Nyström, phone: +46 31 786 2582, e-mail: thomas.nystrom (at) cmb.gu.se Unions Union representatives at the University of Gothenburg: http://www.gu.se/english/about_the_university/job-opportunities/union-representatives How to apply In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application. The application should contain: • A cover letter giving a brief abstractJV_description of previous research experience, and a motivation to why you are applying • A CV including a list of publications • Proof of completed PhD • Contact details of two references The University of Gothenburg promotes equal opportunities, equality and diversity. Salary is determined on an individual basis. Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.   In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.

numberOfPosts: 2

jobCategoriesCodes_0: http://data.europa.eu/esco/isco/C2131

jobCategoriesCodes_1: http://data.europa.eu/esco/isco/C2265

abstractJV_contact_0:
Link to the vacancy on the Swedish job board

requiredEducationLevelCode: 0

requiredYearsOfExperience: 0

positionTypeCode: temporary

contractTypeCodes_0: fulltime

Arbetsgivare Namn: Göteborgs Universitet

source: PES-SWEDEN