Jobbtitel: Discovery Safety Spec/Ass Principal Scientist

Arbetsbeskrivning:

Become a key player in the discovery of innovative medicines.

One of the major challenges in the discovery of innovative medicines is to ensure they are safe enough to test their therapeutic concept in clinical trials and provide novel treatments for patients. Drug safety is assessed throughout the pharmaceutical R&D value chain, but it is during early drug discovery when we can actively design safety attributes into the future candidate drug. Our global Discovery Safety department takes on this challenge and delivers small molecule and oligonucleotide-based drugs with the ?Right Safety? profile. As true Drug Hunting partners to our Innovative Medicines units, we contribute to the selection of novel drug targets, identification and optimization of new chemical series as well as a range of other modalities, and selection of novel candidate drugs. We develop and apply cutting edge in silico, molecular, cellular and in vivo technologies and push the boundaries of predictive safety science with our mission in mind: to discover safe innovative medicines for the patients that need them.

For our team in Gothenburg, Sweden, we are looking for a

Discovery Safety Specialist / Associate Principal Scientist

As Discovery Safety Specialist, you will:

-Contribute to the discovery of innovative treatments for Cardiovascular, Metabolic, Respiratory, Inflammatory and/or Autoimmune diseases.

-Be responsible for the safety strategy in multi-disciplinary drug-hunting project teams. You will lead drug safety teams to influence project decision making with the aim to deliver molecules with the "Right Safety" profile.

-Design project-specific in vitro and in vivo strategies to predict, assess and mitigate target- and drug-related safety risks and execute through internal and external experimental capabilities.

-Engage with world-class experts across our organization to develop, refine and implement innovative experimental strategies and use the data to assess and/or provide mechanistic understanding of safety issues.

-Develop innovative solutions and research proposals to pursue cutting edge science and technologies in order to optimize and influence safety assessment of novel drug targets.

We are looking for candidates with the following profile:

-Excellent scientist, with a PhD in cell biology, toxicology, pharmacology, systems biology or related field, and a strong scientific track record.

-Experience with design and execution of in vitro and/or in vivo experiments to determine the effects of therapeutics on biological systems.

-Solid understanding of the drug discovery and development process based on more than 3 years of experience from the pharmaceutical industry, with an appreciation of disciplines within and outside safety and toxicology, and a track record of successful contributions to progression of drug discovery projects.

-Strong communication, presentation and influencing skills across levels/disciplines.

-Highly motivated, creative, innovative, reliable scientist, with a flexible, collaborative, team-oriented mindset, who solves problems in a goal-focused fashion.

-Knowledge/experience in one or..........

To read FULL JOBDESCRIPTION and to APPLY, read more on www.astrazeneca.se

Arbetsgivare Namn: AstraZeneca Göteborg

Arbetsgivare adress: 43183 MÖLNDAL

Form av kontakt:
titel : telefon 1: () telefon 2: () mobil: e-post:

Arbetsgivare telefonnummer: 031-7761000

Jobb kort beskrivning:
Biologists, botanists, zoologists and related professionals

Land: Sweden

Område: Västra Götalands län

Avtalstid: Permanent

Typ av kontrakt: Full time

Källa till jobberbjudande: Public Employment Service of Sweden(AMS)

Hur man ansöker: Other - see free text